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Methylated Vitamins – Benefits

By Jiri Kaloc

Methylated vitamins are involved in several essential processes in the body so it’s not hard to find ways in which they could be beneficial. Let’s take a closer look at where they do the most important work in the human body and what may be improved if you supplement with them.

Enhanced bioavailability and absorption

Methylated vitamins are already in their active forms, which makes them more readily absorbed and utilized by the body compared to their non-methylated counterparts. Methylated vitamins bypass several metabolic steps that are required for non-methylated vitamins, making them more efficient at reaching and acting in the body’s cells.

Neurological health and mood

Methylated vitamin B12 is crucial for maintaining healthy nerve cells and producing myelin, the protective sheath around nerves. It supports overall nervous system health, mood stability, and may even reduce the risk of neurological disorders and peripheral neuropathy​.

Methylated vitamin B9 plays a role in the production of neurotransmitters serotonin and dopamine that regulate mood and stress. It supports mental health and potentially reduces the risk of neurodegenerative diseases.

Cardiovascular health

Both methylated versions of vitamin B12 and B9 help regulate homocysteine levels in the blood during the methylation cycle. Elevated homocysteine is associated with an increased risk of cardiovascular diseases, so maintaining healthy levels is crucial.

Methylation helps produce glutathione which is the body’s own powerful antioxidant. Oxidative stress contributes to the development of cardiovascular diseases by damaging cells and tissues, so methylated vitamins can indirectly help combat it.

Energy and metabolism

Methylated vitamin B12 is essential for the proper functioning of mitochondria. It plays a critical role in the production of ATP, the primary energy currency of the cell. Both methylated versions of vitamin B12 and B9 are also crucial for the production of red blood cells. Red blood cells transport oxygen from the lungs to the rest of the body, allowing for energy production o happen.

Pregnancy and fetal development

Methylated vitamin B9 is critical for fetal development, particularly in the formation of the neural tube, and can help prevent birth defects like spina bifida.

Genetic variations

Methylated B vitamins are particularly important for individuals with certain genetic variations, such as the MTHFR gene mutation, which can impact the body’s ability to convert regular B vitamins into their active form. By using methylated B vitamins, individuals with these genetic variations can bypass potential conversion issues and ensure optimal absorption and utilization of these essential nutrients. We will take a closer look at this in the next article of this series which will be all about who should supplement methylated vitamins.